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Hydroquinone

Hydroquinone is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical formula C6H4(OH)2. It has two hydroxyl groups bonded to a benzene ring in a para position. Its mechanism of action is through Tyrosinase inhibition. Tyrosinase is the enzyme principally involved in Melanogensis (Melanin production in skin cells).

It works to change the skin-tone by Tyrosinase inhibition. Tyrosinase is a dermal enzyme principally involved in Melanogensis (Melanin production).

Is it safe high percentage Hydroquinone safe?

A study conducted by the FDA on rodents at very high doses (99%) administered by feeding tube showed the potential to be carcinogenic. However, according to same FDA report when used transdermally (topically) absolutely no carcinogenic effects were noted. Studies on humans revealed a very minor risk to develop exogenous ochornosis with extreme prolonged usage.

Conditions approved by the FDA for treatment with hydroquinone

Just some conditions treated using Hydroquinone include:

  • Perma-tans (Perma-tans are deeply set layers of hyper-pigmentation that are very unresponsive to treatment) and uneven skin-tone.
  • Spots and Blemishes like Acne scars, freckles, allergies, insect bites.
  • Scars and patches due to burns, dermatitis, or hormonal imbalances e.g. Melasma or Thyroid disease.